The most highly anticipated regular-season game of the season (and po sibly of all time) is upon us. For the first time since leaving the organization in the spring of 2020 after two-decades of unprecedented succe s, is returning to Foxborough to take on his former team in the and former head coach in Bill Belichick. The 44-year-old quarterback will be rolling into Gillette Stadium with his new squad in the , who are looking to repeat as champions in 2021.In this space, we'll dive Wilmer Flores Jersey into all the different betting angles that this game has for us. We'll take a look at how the spread and total have moved throughout the week leading up to this epic head-to-head and we'll give our picks for this game as well, along with a few player props that catch our eye.Date:Sunday, Oct. 3 |Time:8:20 p.m. ETLocation:Gillette Stadium (Foxborough, Ma sachusetts)TV:NBC|Stream:fuboTV ( )Follow:Odds Neil Walker Jersey :Buccaneers -7, O/U 49.5 Latest Odds: New England Patriots +6.5 The Buccaneers opened as a 5.5-point favorite and that advantage has only increased as the week has gone on. On the eve of this matchup, Tampa Bay is a full 7-point road favorite against the Patriots. The pick: Buccaneers -7.While this is a polarizing matchup thanks to Brady playing his former team, I don't know if this will be particularly competitive. The Buccaneers are simply the better football team and are by a wide margin. Tampa's offensive efficiency ranks inside the top five in the , while New England sits at 26th overall in DVOA, per Football Outsiders. At this stage in his career, it doesn't seem likely that will be able to go toe to toe with Brady, especially with the big discrepancy in talent at the skill positions. Meanwhile, Tampa Bay is 5-0 ATS over its last five games following a straight-up lo s and the Patriots are 2-5 ATS in their last seven overall. Key trend:Buccaneers are 5-1 ATS in their last six games overall New York Mets Jersey . The total for this game largely held at 49 for the bulk of the week, but has begun to tick up as it's now 49.5 as of Saturday afternoon.The pick: Under 49.5. There's a scenario where Brady just lights up the scoreboard to make a statement against his former team and basically takes us the bulk of the way to hitting the Over, but I have little faith in the Patriots' offense being able to match the scoring production. Jones has yet to truly master the deep ball and the protection in front of him hasn't given him much help as of late. Now, he'll face a tough Bucs front seven that should continue to give the offense headaches. Key trend: Under is 7-1 in Patriots' last eight home games. TB QB #12 CMP%68.8YDs1087TD10INT2YD/Att7.71 Pa sing touchdowns:2.5 (Over +110, Under -140)Pa sing yards:304.5 (Over -115, Under -115)Pa s attempts:39.5 (Over -110, Under -120)Completions: 25.5 (Over -120, Under -110)Longest pa s completion: 38.5 (Over -110, Under -120)Interceptions:0.5 (Over -135, Under +105)The Tim Tebow Jersey Over on Brady's completions prop at 25.5 is where I'd lean out of this bunch. The quarterback needs just 68 yards pa sing to be break the NFL record, so he'll likely be dropping back early and often against his former club. It will be interesting to see how the Patriots defend Brady, but he's gone over this number in two of his three games played this season. NE QB #10 CMP%67.5YDs737TD2INT3YD/Att6.14 Pa sing touchdowns: 1.5 (Over -105, Under -125)Pa sing yards: 259.5 (Over -115, Under -115)Pa s attempts:37.5 (Over -125, Under -105)Completions: 25.5 (Over -105, Under 125)Longest pa s completion:35.5 (Over -115, Under -115)Interceptions:0.5 (Over -145, Under +115)I expect the Patriots to be trailing in this game, which is why I like the Over on Jones' 37.5 pa s attempts prop for Jose Reyes Jersey Sunday. New England will likely need to lean on the rookie quarterback to try and throw its way to a victory. Meanwhile, the Buccaneers' secondary isn't particularly dominant, allowing a 72.2 completion percentage and 338.3 pa sing yards per game. Jones has also topped Juan Lagares Jersey this prop in two of his three starts, including last week when he dropped back 51 times. total receptions: Over 5.5 (-130). Meyers saw 14 targets last week and should continue to be a go-to outlet for Jones, especially now that pa sing-down back is on IR. total rushing yards: Over 48.5 (-115). New England is allowing 122.7 rushing yards per game on 4 yards per carry. anytime touchdown (+850). Lottery ticket, but Taylor is poised to take over the third-down back role left by White, which was quite productive through the first three weeks. Taylor is an electrifying back that has the ability to score any time he touches the ball, making this one of the more exciting longshot plays of this game.